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長(cháng)期從事水產(chǎn)動(dòng)物寄生蟲(chóng)的分類(lèi)、系統發(fā)育與進(jìn)化、生活史、生態(tài)以及寄生蟲(chóng)病的流行病學(xué)、致病機理和防控技術(shù)，以及水產(chǎn)動(dòng)物養殖水體、底泥及消化道微生物群落的分子生態(tài)學(xué)、群落結構以及有益微生物制劑的基礎及應用研究。共發(fā)表論文200余篇，SCI收錄100多篇；獲得中國科學(xué)院自然科學(xué)二等獎和武漢市科技進(jìn)步獎各1項，獲得國家發(fā)明專(zhuān)利5項，制定國家行業(yè)標準11項；主編著(zhù)作1部，參編著(zhù)作3部。

代表性論文：

1. Zhao, Weishan; Li, Ming*; Xiong, Fan; Zhang, Dong; Wu, Shangong; Zou,Hong; Li, Wenxiang; Wang, Guitang*; Identification of intracellular bacteria in the ciliate Balantidium ctenopharyngodoni (Ciliophora, Litostomatea), Journalof Eukaryotic Microbiology, 2020, doi:10.1111/jeu.1279: 12.

2. Zhang, Dong; Gao, Fanglun; Jakovli?, Ivan; Zou, Hong; Zhang, Jin; Li,Wenxiang*; Wang, Guitang*; PhyloSuite: an integrated and scalable desktop platform for streamlined molecular sequence data management and evolutionary phylogenetics studies, Molecular Ecology Resources, 2019, 20: 348-355.

3. Hao, Yaotong; Wu, Shangong*; Xiong, Fan; Tran, Ngoc tuan; Jakovli?, Ivan; Zou, Hong; Li, Wenxiang; Wang, Guitang*; Succession and fermentation products of grass carp (Ctenopharyngodon idellus) hindgut microbiota in response to an extreme dietary shift, Frontiers in Microbiology, 2017, 8: 1585.

4. Hao, Yaotong; Wu, Shangong*; Jakovlic, Ivan; Zou, Hong; Li, Wenxiang; Wang, Guitang*; Impacts of diet on hindgut microbiota and short-chain fatty acids in grass carp (Ctenopharyngodon idellus), Aquaculture Research, 2017, 48(11): 5595-5605.

5. Li, Wenxiang; Zhang, Dong; Boyce, Kellyanne; Xi, Bingwen; Zou, Hong; Wu, Shangong; Li ,Ming; Wang Guitang *. The complete mitochondrial DNA of three monozoic tapeworms in the Caryophyllidea: a mitogenomic perspective on the phylogeny of eucestodes. Parasites & Vectors, 2017, 10: 314.

6. Zhang, Xiaoping; Li, Wenxiang; Ai, Taoshan; Zou, Hong; Wu, Shangong; Wang, Guitang *. The efficacy of four common anthelmintic drugs and traditional Chinese medicinal plant extracts to control Dactylogyrus vastator (Monogenea). Aquaculture, 2014, 420-421: 302-307.

7. Xiong, Fan; Li, Wenxiang; Wu, Shangong; Zou, Hong; Wang, Guitang*.  Molecular phylogeny and specificity of the larval Eustrongylides (Nematoda: Dioctophmidae) from freshwater fish in China. J. Parasitol., 2013, 99(1), 137-144.

8. Wu, Shangong; Wang,Guitang*; Angert, Esther R.; Wang, Weiwei; Li, Wenxiang; Zou, Hong. Composition, diversity, and origin of the bacterial community in grass carp intestine, PLoS ONE, 2012, 7(2): e30440.

專(zhuān)利：

1. 王桂堂，楊寶娟，李文祥，鄒紅，吳山功. 一種草魚(yú)鰓部寄生鰓片指環(huán)蟲(chóng)的特異性擴增引物對及其應用（ZL201410118871.3）

2. 鄒紅，熊凡，張金，李文祥，吳山功，王桂堂. 一種柱狀黃桿菌的檢測試劑盒及檢測方法(ZL201510578122.3)

3. 王桂堂，熊凡，吳山功， 鄒紅，李文祥. 一種纖維素酶生產(chǎn)菌及其應用(ZL201510267129.3)

4. 鄒紅，熊凡，張金，李文祥，吳山功，王桂堂. 遲緩愛(ài)德華氏菌的檢測試劑盒及其應用（ZL 201610316398.9）

5. 王桂堂，趙威山，李明，吳山功，鄒紅，李文祥，熊凡. 一種鯇腸袋蟲(chóng)的體外培養方法及使用的培養基的制備方法（ZL 201810350529.4）

論著(zhù)：

1. 王桂堂，李文祥，鄒紅，李明，吳山功。淡水魚(yú)類(lèi)重要寄生蟲(chóng)病診斷手冊?？茖W(xué)出版社，2017。

2. 王桂堂參編。魚(yú)病學(xué)，負責寄生蠕蟲(chóng)及蠕蟲(chóng)病、寄生甲殼動(dòng)物及甲殼動(dòng)物病部分（164頁(yè)）。中國農業(yè)出版社，2013。

3. 王偉俊，朱心玲，王桂堂，姚衛建。淡水魚(yú)病防治彩色圖說(shuō)。中國農業(yè)出版社， 2001。

4. 汪建國，王桂堂，盧全章，李?lèi)?ài)華，張奇亞。養殖魚(yú)類(lèi)疾病防治技術(shù)。鄭州：中原農民出版社，1998。