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        童金茍　研究員
        博士研究生
        
						  
        
							
        
								
        
							
        
							
        
								
        
                                    
        
                                            
                                              
        
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                                                研究員
                                              
        
                                              
        
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           童金茍，1961年出生于湖北武漢，博士研究生導師；曾訪(fǎng)問(wèn)澳大利亞海洋研究所、皇家墨爾本理工大學(xué)，在香港中文大學(xué)進(jìn)行1年博士后研究。1985年以來(lái)在中國科學(xué)院水生生物研究所工作至今，從事鯉科魚(yú)類(lèi)遺傳學(xué)和育種研究，主要研究?jì)热菔菑姆肿尤后w遺傳學(xué)和基因組學(xué)、細胞遺傳學(xué)、功能基因組等層面，解析鳙（胖頭魚(yú)）等魚(yú)類(lèi)生長(cháng)和體型等主要經(jīng)濟性狀的遺傳基礎，開(kāi)展快速馴化、遺傳選育和分子設計育種，為培育符合市場(chǎng)需求的魚(yú)類(lèi)養殖新品種（系）并推廣養殖奠定基礎。先后主持承擔國家“973”子課題、課題，國家重點(diǎn)研發(fā)計劃課題，國家自然科學(xué)基金，公益性（農業(yè)）科研專(zhuān)項子課題，中科院戰略性先導科技專(zhuān)項子課題，中科院STS區域重點(diǎn)等國家和省部級科研項目，以及一批其它課題；發(fā)表國內外核心刊物論文100余篇（SCI收錄約70篇）；獲授權專(zhuān)利3項。
         
        研究方向
        魚(yú)類(lèi)遺傳學(xué)與分子育種，魚(yú)類(lèi)分子群體遺傳學(xué)與基因組學(xué)，魚(yú)類(lèi)細胞遺傳學(xué)及育種生物技術(shù)
         
        代表性論著(zhù)
         
        1.   Zhou Y, Fu BD, Yu XM*, Chen J, Wang JR, Luo WW, Feng YZ, Tong J*. 2021. Genome-wide association study reveals genomic regions and candidate genes for head size and shape in bighead carp (Hypophthalmichthys nobilis). Aquaculture, 539: 736648
        2.   Luo WW, Zhou Y, Wang JR, Yu XM*, Tong J*. 2020. Identifying candidate genes involved in the regulation of early growth using full-length trancscriptome and RNA-seq analyses of frontal and parietal bones and vertebral bones in bighead carp (Hypophthalmichthys nobilis). Front Genet, 11: 603454
        3.   Luo WW, Wang JR, Yu XM, Zhou Y, Tong J*. 2020. Comparative transcriptome analyses and identification of candidate genes involved in vertebral abnormality of bighead carp Hypophthalmichthys nobilis. Comp Biochem Physiol D Genom Proteom, 36:100752 
        4.   Zhou Y, Luo WW, Yu XM*, Wang JR, Feng YZ, Tong J.* 2020. Cardiac transcriptomics reveals that MAPK pathway plays an important role in hypoxia tolerance in bighead carp (Hypophthalmichthys nobilis). Animals, 10: 1483  
        5.   Zhou Y, Tong J, Wang JR, Yu XM*. 2020. Development of microsatellite markers and genetic diversity in wild and cultured populations of black carp (Mylopharyngodon piceus) along the Yangtze River. Aquaculture Int, 28: 1867-1882.
        6.   Zhou Y, Liu HY, Wang XH, Fu BD, Yu XM, Tong J*. 2020. QTL fine mapping for sex determination region in bighead carp (Hypophthalmichthys nobilis) and comparison with silver carp (Hypophthalmichthys molitrix). Mar Biotechnol, 22: 41–53
        7.   Wang XH, Liu HY, Pang MX, Fu BD, Yu XM, He SP, Tong J*. 2019. Construction of a high-density genetic linkage map and growth-related quantitative trait loci mapping in silver carp (Hypophthalmichthys molitrix). Sci Rep, 9:17506 
        8.   Cheng WW, Yu XM, Yang K*., Tong J*., Zhu SH, Wang QY, Xia YL, Li B, Fu BD, Deng GQ. 2019. Meiotic gynogenesis with heterologous sperm in the mandarin fish Siniperca chuatsi and evidence for female homogamety, Aquaculture Res, 50:3286–3294. 
        9.   Fu BD，Yu XM，Tong J*, Pang MX, Zhou Y, Liu QS, Tao WJ. 2019. Comparative transcriptomic analysis of hypothalamus-pituitary-liver axis in bighead carp (Hypophthalmichthys nobilis) with differential growth rate. BMC Genomics, 20: 328
        10.   Zhou Y, Luo WW, Yu XM, Liu QS, Tong J.* 2019. Brain and intestine transcriptome analyses and identification of genes involved in feed conversion efficiency of Yellow River carp (Cyprinus carpio haematoperus). Comp Biochem Physiol D Genom Proteom, 29: 221-227.
        11.   Feng Xiu, Yu X.M., Pang M.X. Tong J.* 2019. Molecular characterization and expression regulation of the factor inhibiting HIF-1 (FIH-1) gene under hypoxic stress in bighead carp (Aristichthys nobilis). Fish Physiol Biochem, 45: 657-65. 
        12. Feng X, Yu XM, Fu BD, Wang XH, Liu HY, Pang MX, Tong J*. 2018. A high-resolution genetic linkage map and QTL fine mapping for growth-related and sex in the Yangtze River common carp (Cyprinus carpio haematopterus). BMC Genomics, 19: 230
        13. Pang MX, Luo WW, Fu BD, Yu X, Zhou Y, Tong J*. 2018. Transcriptomic profiles of brain provide insights into molecular mechanism of feed conversion efficiency in crucian carp (Carassius auratus). Int J Mol Sci, 19: 858
        14.   Pang MX, Tong J*,Yu X, Fu BD, Zhou Y. 2018. Molecular cloning, expression pattern of follistatin gene and association analysis with growth in bighead carp (Hypophthalmichthys nobilis). Comp Biochem Physiol Part B: Biochem Mol Biol, 218: 44-53.  
        15.   Liu HY, Pang MX, Yu XM, Zhou Y, Tong J, Fu BD*. 2018. Sex-specific markers developed by next generation sequencing confirmed an XX/XY sex determination system in bighead carp (Hypophthalmichthys nobilis) and silver carp (Hypophthalmichthys molitrix). DNA Res, 25: 257-254
        16. Wang X.H., Fu B.D., Yu X., Qu C.Y., Zhang Q., Tong J.* 2018. Fine mapping of growth-related quantitative trait loci in Yellow River carp (Cyprinus carpio haematoperus).  Aquaculture, 484: 277-285.  
        17. Pang M.X., Fu B.D., Yu M., Liu H.Y., Wang X.H., Yin Z., Xie S.Q., Tong J.* 2017. Quantitative trait loci mapping for feed conversion efficiency in crucian carp (Carassius auratus). Sci Rep, 7:16971.
        18. Liu H.Y., Fu B.D., Pang M.X., Feng X., Yu X., Tong J.* 2017. A high-density genetic linkage map and QTL fine mapping for body weight in crucian carp (Carassius auratus) using 2b-RAD sequencing. G3: Genes Genomes Genetics, 7: 2473-2487.
        19. Wang XH, Yu X, Tong J.* 2016. Molecular characterization and growth association of two Apolipoprotein AIb genes in common carp (Cyprinus carpio). Int J Mol Sci, 17:1569
        20. Liu HY, Fu BD, Pang MX, Feng X, Wang XH, Yu XM, Tong J.* 2016. QTL fine mapping and identification of candidate genes for growth-related traits in bighead carp (Hypophthalmichthys nobilis). Aquaculture, 465: 134-143.  
        21. Fu B.D., Liu H.Y, Yu X.M, Tong J*. 2016. A high-density genetic map and growth-related QTL mapping in bighead carp (Hypophthalmichthys nobilis). Sci Rep, 6: 28679 
        22. Zhu C., Tong J.*, Yu X., Guo W.J. 2015. Comparative mapping for bighead carp (Aristichthys nobilis) against model and non-model fishes provides insights into the genomic evolution of cyprinids. Mol Genet Genomics, 290: 1313-1326    
        23. Feng X., Wang X.H., Yu X., Zhang X.F., Lu C.Y., Sun X.W., Tong J.* 2015. Microsatellite-centromere mapping in common carp through half-tetrad analysis in diploid meio-gynogenetic families. Chromosoma, 124(1): 67-79. 
        24. Tong J.*, Sun X. 2015. Genetic and genomic analyses for economically important traits and their applications in molecular breeding of cultured fish. Sci China: Life Sci, 58 (2): 178–186.
        25. 童金茍*，孫效文. 魚(yú)類(lèi)經(jīng)濟性狀遺傳解析及分子育種應用研究. 中國科學(xué):生命科學(xué), 2014, 44(12)：1262-1271
        26. Zhu C., Tong J.*, Yu X., Guo W., Wang X., Liu H., Feng X., Sun Y., Liu L., Fu B. 2014. A second-generation genetic linkage map for bighead carp (Aristichthys nobilis) based on microsatellite markers. Anim Genet, 45: 699-708
        27. Zhu C.K., Sun Y.H., Yu X.M. Tong J.* 2013. Centromere localization for bighead carp (Aristichthys nobilis) through half-tetrad analysis in diploid gynogenetic families. PloS One, 8(12): e82950. (SCI) 
        28. Guo W., Tong J.*, Yu X., Zhu C., Feng X., Fu B., He S., Zeng F., Wang X., Liu H., Liu L. 2013. A second generation genetic linkage map for silver carp (Hypophthalmichthys molitrix) using microsatellite markers. Aquaculture, 412-413: 97-106
        29. Zhu C., Yu X., Fu B., Tong J.* 2013. Development of 201 tri- and tetra-nucleotide repeat microsatellites for bighead carp (Aristichthys nobilis). Conserv Genet Resour, 5:755-758
        30. Sun Y.H., Yu T., Tong J.* 2012. Polymorphisms in myostatin gene and associations with growth traits in common carp. Int J Mol Sci, 13: 14956-14961
        31. Liu L., Yu X., Tong J.* 2012. Molecular characterization of myostatin (MSTN) gene and association analysis with growth traits in the bighead carp (Aristichthys nobilis). Mol Biol Rep, 39: 9211–9221
        32. Zhu C., Cheng L., Tong J.*, Yu X. 2012. Development and characterization of new single nucleotide polymorphism markers from expressed sequence tags in common carp (Cyprinus carpio). Int J Mol Sci, 13: 7343-7353
        33. 譚新，童金茍*. 2011. SNPs及其在水產(chǎn)動(dòng)物遺傳學(xué)與育種學(xué)研究中的應用. 水生生物學(xué)報，35: 348-354.
        34. Cheng L., Liu L., Yu X., Wang D., and Tong J.* 2009. A linkage map of common carp (Cyprinus carpio) based on AFLP and microsatellite markers. Anim Genet, 41:191-198