職 稱: | 研究員 |
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學 歷: | 博士研究生 |
聯(lián)系方式: | 86-027-68780685 |
電子郵件: | bob#ihb.ac.cn(請改#為@) |
辦 公 室: | 2號實驗樓1013 |
個人網(wǎng)頁: |
2003-2007年 武漢大學 生命科學學院 理學學士 2007-2012年 中國科學院水生生物研究所 水生生物學專業(yè) 理學博士 |
2012-2016年 中國科學院水生生物研究所 助理研究員 2016年至今 中國科學院水生生物研究所 副研究員 |
水產(chǎn)養(yǎng)殖(碩士生,博士生) |
魚類病毒與宿主相互作用關(guān)系、抗病毒漁藥開發(fā) |
主持國家優(yōu)秀青年科學基金、國家自然科學面上基金、國家自然科學青年基金、中科院青年促進會、國家重點開發(fā)計劃子課題等。 |
以第一或通訊作者身份在PLoS Pathogens、Journal of Immunology、Journal of Virology等國際主流期刊上發(fā)表SCI論文31篇,且先后4次被Journal of Immunology撰寫專欄重點推薦。抗病毒技術(shù)成果轉(zhuǎn)化1項。
代表性論文: 第一作者或通訊作者文章: 1. Long-Feng Lu#, et al., Shun Li, Fish female-biased gene cyp19a1a leads to female antiviral response attenuation between sexes by autophagic degradation of MITA, PLoS Pathogens, 2022, 18:e1010626. 2. Long-Feng Lu, et al., Shun Li, A novel role of Zebrafish TMEM33 in negative regulation of interferon production by two distinct mechanisms, PLoS Pathogens, 2021, 17:e1009317. 3. Shun Li#, et al., Spring viraemia of carp virus modulates p53 expression using two distinct mechanisms, PLoS Pathogens, 2019, 15:e1007695. 4. Xue-Li Wang, et al., Long-Feng Lu#, Shun Li#, SVCV N Protein Negatively Regulates Interferon Induction Through Autophagy-Lysosome-Dependent Degradation of STING, Journal of Immunology, 2023, 210(1):72-81. 5. Dan-Dan Chen, et al., Shun Li, Zebrafish Uba1 degrades IRF3 through K48-linked ubiquitination to inhibit IFN production, Journal of Immunology, 2021, 207:512-522. 6. Dan-Dan Chen, et al., Shun Li, Zebrafish CERKL Enhances Host TBK1 Stability and Simultaneously Degrades Viral Protein via Ubiquitination Modulation. Journal of Immunology, 2022, 208:2196-2206. 7. Long-Feng Lu, et al., Shun Li, Zebra?sh RBM47 promotes lysosome-dependent degradation of MAVS to inhibit IFN induction, Journal of Immunology, 2020, 205(7):1819-1829. 8. Shun Li#, Long-Feng Lu#, et al., Zebrafish MVP recruits and degrades TBK1 to suppress IFN production, Journal of Immunology, 2019, 202:559-566. 9. Long-Feng Lu#, Shun Li#, et al., Spring viremia of carp virus N protein suppresses fish IFNφ1 production by targeting the mitochondrial antiviral signaling protein, Journal of Immunology, 2016, 196:3744-3753. 10. Shun Li, et al., IFN regulatory factor 10 is a negative regulator of the IFN responses in fish, Journal of Immunology, 2014, 193:1100-1109. 11. Long-Feng Lu, et al., Shun Li, Zebrafish TMEM47 is an effective blocker of IFN production during RNA and DNA virus infection, Journal of Virology, 2023, (Accepted). 12. Can Zhang, et al., Feng Ge#, Shun Li#, Zebrafish MAP2K7 Simultaneously Enhances Host IRF7 Stability and Degrades Spring Viremia of Carp Virus P Protein via Ubiquitination Pathway, Journal of Virology, 2023, 97(7):e0053223. 13. Long-Feng Lu, et al., Shun Li, Zebrafish RPZ5 degrades the phosphorylated IRF7 to repress interferon production, Journal of Virology, 2019, 93(21):e01272-19. 14. Shun Li, et al., The P protein of spring viremia of carp virus negatively regulates the fish interferon response by inhibiting the kinase activity of TANK-binding kinase 1, Journal of Virology, 2016, 90:10728-10737.
成果轉(zhuǎn)化: 《金屬離子在制備防治水生病毒感染的藥物中的應用》,100萬元。 |
在讀研究生: 王雪麗(2020級碩士)、韓珂佳(2021級碩士) 畢業(yè)研究生: 李卓聰(2018級碩士,2021年春季轉(zhuǎn)博) 張燦(2018級碩士,2021年畢業(yè)后考入水生所讀博) 周小雨(2018級聯(lián)培碩士,2021年畢業(yè)后考入水生所讀博) 江婧宇(2019級碩士,2021年秋季轉(zhuǎn)博) 研究生獲獎: 2019年李卓聰獲得中科院研究生獎學金碩士一等獎 |